Intracellular Fates of Cell-Penetrating Block Copolypeptide Vesicles
نویسندگان
چکیده
منابع مشابه
Blending of diblock and triblock copolypeptide amphiphiles yields cell penetrating vesicles with low toxicity.
We prepared dual hydrophilic triblock copolypeptide vesicles that form both micron and nanometer scale vesicles in aqueous media. The incorporation of terminal homoarginine segments into methionine sulfoxide-based vesicles was found to significantly enhance their cellular uptake compared to a non-ionic control. We also demonstrated that diblock and triblock copolypeptides with similar hydrophob...
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ژورنال
عنوان ژورنال: Biomacromolecules
سال: 2011
ISSN: 1525-7797,1526-4602
DOI: 10.1021/bm101036f